Protein Phosphorylation: Hyperbolic

Publication

Tyson, J. J., Chen, K. C., & Novak, B. (2003).
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.
Current opinion in cell biology, 15(2), 221-231.

PMID: 12648679   DOI: 10.1016/S0955-0674(03)00017-6

Description

This ModelBrick from the article, “Sniffers, buzzers, toggles and blinkers…” describes protein phosphorylation and dephosphorylation, yielding a hyperbolic signal-response curve.

Reaction Diagram

Images

SBGN visualization Publication: Simulation

Downloads

  VCell ModelBrick download model (.vcml) Designed with VCell
  SBML CM_PM12648679_MB2A.xml Exported from VCell
  GraphML CM_PM12648679_MB2.graphml Designed with yED
  SBGN-ML CM_PM25628036_MB2.sbgn Converted with ySBGN

Contributors

Michael Blinov