Publication

Stites, E. C., Aziz, M., Creamer, M. S., Von Hoff, D. D., Posner, R. G., & Hlavacek, W. S. (2015).
Use of mechanistic models to integrate and analyze multiple proteomic datasets.
Biophysical journal, 108(7), 1819-1829.

PMID:25863072  DOI: 10.1016/j.bpj.2015.02.030

Description

This model describes the binding and phosphorylation of EGFR by many different proteins which can bind to six different receptors. This ModelBrick describes the binding of proteins to the 1016 receptor.

Images

VCell: reaction diagram VCell: reaction diagram

Downloads

  VCell ModelBrick CM_PM25863072_Y1016.vcml Exported from VCell
  BioNetGen file CM_PM25863072_Y1016.bngl Exported from VCell

Contributors

Bushrah Khan, Riley Steinberg, Michael Blinov