Publication

Stites, E. C., Aziz, M., Creamer, M. S., Von Hoff, D. D., Posner, R. G., & Hlavacek, W. S. (2015).
Use of mechanistic models to integrate and analyze multiple proteomic datasets.
Biophysical journal, 108(7), 1819-1829.

PMID:25863072  DOI: 10.1016/j.bpj.2015.02.030

Description

This model describes the binding and phosphorylation of EGFR by many different proteins which can bind to six different receptors. This ModelBrick describes the binding of proteins to the 1197 receptor.

The curated model

VCell: reaction diagram VCell: reaction diagram

Downloads

VCell curated model CM_PM25863072_Y1197.vcml Designed with VCell
BNGL CM_PM25863072_Y1197.bngl Exported from VCell

Contributors

Bushrah Khan, Riley Steinberg, Michael Blinov